Presurgical infant orthopaedic (PSIO) protocol is applied prior to cleft Lip and/cleft palate surgical intervention to facilitate the repair by restoring the alar base and maintaining the skeletal, soft tissue harmony. The objective of this review is to assess the literature on the presurgical infant orthopaedic protocol most widely used and accepted. Searches were made in PubMed, Cochrane and Google Scholar on cleft lip and/palate. A large number of articles documented approaching PSIO for cleft treatment with the intent to provide a satisfactory treatment for cleft patients, requiring far more than just correctional surgery and its ability to do so is unique. Craniofacial Orthodontists can choose from a wide array of treatment options for their patients and can learn from the outcomes attained by applying a combination of outcomes at various other centers.

Mohammad Zeinalddin is a Consultant Craniofacial Orthodontist and Chief Executive Officer of Mohammad Orthodontic Center LLC, a multidisciplinary dental center in the Sultanate of Oman. He earned his Bachelor of Dental Surgery (BDS) in Oman, followed by a Master of Science in Orthodontics in the United Arab Emirates. He obtained the Membership in Orthodontics (MOrth) from the Royal College of Surgeons of Edinburgh, United Kingdom, and completed a fellowship in Craniofacial Orthodontics in Taiwan. He also holds a certificate in Dental Implantology from Sri Lanka and an MBA in Healthcare Management from the United States. Dr. Zeinalddin serves as a Board Member of the Omani Craniofacial and Cleft Society and is actively involved in advancing interdisciplinary care and professional education. His clinical and research interests include digital orthodontics, artificial intelligence in dentistry, craniofacial anomalies, cleft lip and palate management, orthognathic surgery, and airway focused orthodontics. He has authored and co authored several peer reviewed scientific publications, serves as a reviewer for international orthodontic journals, and has delivered invited lectures at regional and international scientific meetings.